The National Science Foundation approved our MRI proposal for the acquisition of a cryoprobe-equipped 500 MHZ NMR spectrometer! Dr. Bonizzoni serves as one of the co-PIs on this proposal, together with Profs. Paul Rupar (PI), Elizabeth Papish (coPI), Jason Bara (coPI, Dept. of Chemical and Biological Engineering), and Lukasz Ciesla (coPI, Dept. of Biology). The new instrument will replace one of our current departmental NMR spectrometers; it will provide significantly higher sensitivity and automated acquisition capabilities, shortening experiment times and easing the bottleneck for NMR characterization for the many groups in our department that are heavy users of NMR spectroscopy. Our group will first use the new instrument to study the non-covalent complexation of small-molecule organic guests to oligomeric and polymeric carbohydrates (e.g. cyclodextrins, starches) through binding titrations in water. We are very excited to acquire this new capability, which is projected to come online in early to mid-2020.
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